AED 3,128 Cheap flights from Prague to Santiago

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Flight deals from Prague to Santiago

Looking for a cheap last-minute deal or the best round-trip flight from Prague to Santiago? Find the lowest prices on one-way and round-trip tickets right here.

Santiago.AED 3,128 per passenger.Departing Thu, Feb 19, returning Tue, Mar 3.Round-trip flight with LOT and jetBlue.Outbound indirect flight with LOT, departing from Prague on Thu, Feb 19, arriving in Santiago.Inbound indirect flight with jetBlue, departing from Santiago on Tue, Mar 3, arriving in Prague.Price includes taxes and charges.From AED 3,128, select.

Santiago.AED 3,315 per passenger.Departing Thu, Feb 19, returning Sat, Feb 28.Round-trip flight with Wizz Air UK and Spirit Airlines.Outbound indirect flight with Wizz Air UK, departing from Prague on Thu, Feb 19, arriving in Santiago.Inbound indirect flight with Spirit Airlines, departing from Santiago on Sat, Feb 28, arriving in Prague.Price includes taxes and charges.From AED 3,315, select.

Santiago.AED 3,387 per passenger.Departing Mon, Jun 1, returning Mon, Jun 8.Round-trip flight with Delta.Outbound indirect flight with Delta, departing from Prague on Mon, Jun 1, arriving in Santiago.Inbound indirect flight with Delta, departing from Santiago on Mon, Jun 8, arriving in Prague.Price includes taxes and charges.From AED 3,387, select.

Santiago.AED 3,424 per passenger.Departing Sun, Apr 19, returning Sat, May 2.Round-trip flight with Ryanair and jetBlue.Outbound indirect flight with Ryanair, departing from Prague on Sun, Apr 19, arriving in Santiago.Inbound indirect flight with jetBlue, departing from Santiago on Sat, May 2, arriving in Prague.Price includes taxes and charges.From AED 3,424, select.

Santiago.AED 3,688 per passenger.Departing Sat, Sep 12, returning Sat, Sep 19.Round-trip flight with Finnair and jetBlue.Outbound indirect flight with Finnair, departing from Prague on Sat, Sep 12, arriving in Santiago.Inbound indirect flight with jetBlue, departing from Santiago on Sat, Sep 19, arriving in Prague.Price includes taxes and charges.From AED 3,688, select.

Santiago.AED 5,209 per passenger.Departing Mon, Jun 29, returning Thu, Jul 9.Round-trip flight with Norwegian and jetBlue.Outbound indirect flight with Norwegian, departing from Prague on Mon, Jun 29, arriving in Santiago.Inbound indirect flight with jetBlue, departing from Santiago on Thu, Jul 9, arriving in Prague.Price includes taxes and charges.From AED 5,209, select.

Santiago.AED 5,285 per passenger.Departing Sat, Jul 4, returning Wed, Jul 8.Round-trip flight with Finnair and Air Europa.Outbound indirect flight with Finnair, departing from Prague on Sat, Jul 4, arriving in Santiago.Inbound indirect flight with Air Europa, departing from Santiago on Wed, Jul 8, arriving in Prague.Price includes taxes and charges.From AED 5,285, select.

Find the cheapest month to fly from Prague to Santiago

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Prague to Santiago flights are currently cheapest in February.

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Prague to Santiago: Alternative routes

Compare routes from Prague to Santiago below. You may find an airport to fly into that's cheaper, faster, or easier than Santiago.

Santiago

2km from central Santiago

ClosestCheapest

from AED 3,128

Search flights

Puerto Plata

37km from central Santiago

from AED 3,389

Search flights

Prague to Santiago: Flight information

The things to know before you go.

Cheapest flight found	AED 3,128
Cheapest month to fly	February

Check out these Santiago hotels

Ready to plan your stay? Other travelers rate these Santiago hotels for cleanliness, service, and location.

Hotel Santiago, Curio Collection By Hilton

1.88 km from Santiago

‎AED 576

Per night

Nohian Collection Hotels

1.28 km from Santiago

‎AED 522

Per night

Hodelpa Gran Almirante

1.47 km from Santiago

‎AED 512

Per night

Hotel Santiago, Curio Collection By Hilton

1.88 km from Santiago

‎AED 576

Per night

Nohian Collection Hotels

1.28 km from Santiago

‎AED 522

Per night

Hodelpa Gran Almirante

1.47 km from Santiago

‎AED 512

Per night

Explore top-rated hotels

Finding cheap flights from Prague to Santiago: Frequently asked questions

How much are round-trip flights from Prague to Santiago?

The best price we found for a round-trip flight from Prague to Santiago is AED 3,128. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.

Which airlines fly direct from Prague to Santiago?

Currently, there are no airlines that fly direct from Prague to Santiago. But we found flights with one or more stops from AED 3,128.

How many flights are there a week from Prague to Santiago?

There are no flights flying from Prague to Santiago, as of February 2026.

When is the cheapest time to fly from Prague to Santiago?

The cheapest month to fly from Prague to Santiago is usually February.

Which upcoming date is cheapest to fly from Prague Airport to Santiago Airport on?

After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Prague Airport to Santiago Airport on Thursday, February 19, 2026.

Can I get a direct flight from Prague Airport to Santiago Airport?

No airlines currently offer direct flights between Prague Airport and Santiago Airport. Most routes have one or more stops.

When is the best time to book flights to Santiago?

We crunched all the numbers in our flight calendar, and it looks like the cheapest time to book a flight to Santiago is around 40 days in advance, so don’t leave your flight to the last minute.

Which is the cheapest airline to fly with from Prague Airport to Santiago?

Currently, LOT offers the cheapest flight tickets to Santiago.

How to find cheap flights from Prague to Santiago

Looking for cheap flight tickets from Prague to Santiago? Skyscanner compares flight prices across more than 1,200 airlines and travel providers.

Regardless of whether you're looking for a one-way ticket to Santiago or a return flight, here are some tips to secure the best flight price and make planning your journey as smooth as possible.

Simply hit search. From Emirates and Etihad to international carriers like Air India and Wizz Air, we compare all major airlines with the most popular online travel agents to find the cheapest plane tickets from Prague to Santiago. And with us there are no hidden fees - what you see is what you pay.

Flex your dates to find the cheapest PRG - STI flight tickets on Skyscanner. Search for flights but don’t enter the departure date and instead click ‘whole month’. This tool will find the cheapest month and dates to fly to Santiago from Prague.

Set up a Price Alert for Prague-Santiago flight tickets. You can easily track the fare of flights by creating an alert. Whenever prices go down or up, you'll get an email to help make sure you get the best possible flight deal. Or download our app and get price alerts straight to your phone.

Fly without stops. Only interested in direct flights between Prague and Santiago? Make sure to tick 'Non-stop flights only' when performing a search. If there are direct flights available on the route, these will appear in the results.

Hotels in Santiago

Looking for a hotel in Santiago? Whether you’re looking for a local hotel or a global brand, discover the best prices and exclusive rates for hotels in Santiago by comparing the biggest names in travel.

Car hire in Santiago

If you’re looking for car rental in Santiago, we can help you uncover the best car hire deals. We search hundreds of car hire companies allowing you to instantly compare prices and then book.

Book flight tickets from Prague to Santiago with extra peace of mind

Back in 2020, most airlines introduced policies to make travel during COVID-19 as easy as possible. The worst of the pandemic is now over, but some of these policies remain in place for you to take advantage of as you step back out into the world.

Find flexible getaways. Some airlines introduced flexible booking policies in 2020 – and many of these are still available. If you book a flexible plane ticket from Prague to Santiago, it means your money is still safe if your flights are changed or cancelled due to COVID-19.

Get insured. Choose travel cost protection that covers COVID-19, too. It's available at the checkout as you book your flight from Prague to Santiago with us.