Cheap Flights from Des Moines to St Louis

Compare Des Moines to St Louis flight deals

Find the cheapest month or even day of the year to fly to St Louis

Book the best St Louis fare with no extra fees

Flight deals from Des Moines to St Louis

Looking for a cheap last-minute deal or the best round-trip flight from Des Moines to St Louis? Find the lowest prices on one-way and round-trip tickets right here.

Find the cheapest month to fly from Des Moines to St Louis

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Des Moines to St Louis flights are currently cheapest in November.

Direct flights from Des Moines to St Louis

Des Moines to St Louis: Alternative routes

Compare routes from Des Moines to St Louis below. You may find an airport to fly into that's cheaper, faster, or easier than St Louis.

Des Moines to St Louis: Flight information

The things to know before you go.
Cheapest flight foundAED 649
Cheapest month to flyNovember
Average flight time1 hr, 11 mins
Most popular airlineSouthwest Airlines
Average flights per week16

Finding cheap flights from Des Moines to St Louis: Frequently asked questions

The best price we found for a round-trip flight from Des Moines to St Louis is AED 650. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
1 hour and 11 minutes is the average flight time from Des Moines to St Louis.
Southwest Airlines flies direct from Des Moines to St Louis.
There are 16 flights per week flying from Des Moines to St Louis, as of October 2024.
The cheapest month to fly from Des Moines to St Louis is usually October 2024.
After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Des Moines Airport to St Louis Airport on Thursday, November 28, 2024.
Yes – the average flight time is 1 hour and 11 minutes.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to St Louis but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar, and it looks like the cheapest time to book a flight to St Louis is around 40 days in advance, so don’t leave your flight to the last minute.
Currently, Delta and Southwest Airlines offer the cheapest flight tickets to St Louis.

How to find cheap flights from Des Moines to St Louis

Looking for cheap flight tickets from Des Moines to St Louis? Skyscanner compares flight prices across more than 1,200 airlines and travel providers.

Regardless of whether you're looking for a one-way ticket to St Louis or a return flight, here are some tips to secure the best flight price and make planning your journey as smooth as possible.

  • Simply hit search. From Emirates and Etihad to international carriers like Air India and Wizz Air, we compare all major airlines with the most popular online travel agents to find the cheapest plane tickets from Des Moines to St Louis. And with us there are no hidden fees - what you see is what you pay.

  • Flex your dates to find the cheapest DSM - STL flight tickets on Skyscanner. Search for flights but don’t enter the departure date and instead click ‘whole month’. This tool will find the cheapest month and dates to fly to St Louis from Des Moines.

  • Set up a Price Alert for Des Moines-St Louis flight tickets. You can easily track the fare of flights by creating an alert. Whenever prices go down or up, you'll get an email to help make sure you get the best possible flight deal. Or download our app and get price alerts straight to your phone.

  • Fly without stops. Only interested in direct flights between Des Moines and St Louis? Make sure to tick 'Non-stop flights only' when performing a search. If there are direct flights available on the route, these will appear in the results.

Hotels in St Louis

Looking for a hotel in St Louis? Whether you’re looking for a local hotel or a global brand, discover the best prices and exclusive rates for hotels in St Louis by comparing the biggest names in travel.

Car hire in St Louis

If you’re looking for car rental in St Louis, we can help you uncover the best car hire deals. We search hundreds of car hire companies allowing you to instantly compare prices and then book.

Book flight tickets from Des Moines to St Louis with extra peace of mind

Back in 2020, most airlines introduced policies to make travel during COVID-19 as easy as possible. The worst of the pandemic is now over, but some of these policies remain in place for you to take advantage of as you step back out into the world.

  • Find flexible getaways. Some airlines introduced flexible booking policies in 2020 – and many of these are still available. If you book a flexible plane ticket from Des Moines to St Louis, it means your money is still safe if your flights are changed or cancelled due to COVID-19.

  • Get insured. Choose travel cost protection that covers COVID-19, too. It's available at the checkout as you book your flight from Des Moines to St Louis with us.

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.