Cheap Flights from Chicago O'Hare International to Knoxville

Compare Chicago O'Hare International to Knoxville flight deals

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Flight deals from Chicago O'Hare International to Knoxville

Looking for a cheap last-minute deal or the best round-trip flight from Chicago O'Hare International Airport to Knoxville Airport? If you want to travel next month, round-trip fares start from AED 834. Find the lowest prices on one-way and round-trip tickets right here.

Find the cheapest month to fly from Chicago O'Hare International to Knoxville

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Chicago O'Hare International to Knoxville flights are currently cheapest in September.

Direct flights from Chicago O'Hare International to Knoxville

Chicago O'Hare International to Knoxville: Alternative routes

Compare routes from Chicago O'Hare International to Knoxville below. You may find an airport to fly into that's cheaper, faster, or easier than Knoxville.

Chicago to Knoxville: Flight information

The things to know before you go.
Cheapest flight foundAED 410
Cheapest month to flySeptember
Average flight time1 hr, 50 mins
Most popular airlineAmerican Airlines
Average flights per week324

Finding cheap flights from Chicago O'Hare International to Knoxville: Frequently asked questions

The best price we found for a round-trip flight from Chicago O'Hare International to Knoxville is AED 818. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
1 hour and 50 minutes is the average flight time from Chicago O'Hare International to Knoxville.
American Airlines, United and SkyWest Airlines fly direct from Chicago O'Hare International to Knoxville.
There are 324 flights per week flying from Chicago O'Hare International to Knoxville, as of May 2026.
The cheapest month to fly from Chicago O'Hare International to Knoxville is usually July.
After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Chicago O'Hare International Airport to Knoxville Airport on Saturday, July 18, 2026.
Yes – the average flight time is 1 hour and 50 minutes.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Knoxville but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar, and it looks like the cheapest time to book a flight to Knoxville is around 40 days in advance, so don’t leave your flight to the last minute.
Currently, Frontier Airlines and American Airlines offer the cheapest flight tickets to Knoxville.

Traveling from O'Hare International Airport (ORD) to McGhee Tyson Airport (TYS): what you need to know

  • Around 1 hour 45 minutes is how long you'll be traveling on a direct flight from O'Hare International Airport to McGhee Tyson Airport.

  • Choose from 71 weekly O'Hare International Airport to McGhee Tyson Airport flights. The 07:10 departure with United Airlines is the earliest you can take. United Airlines operates the latest service of the day at 21:08.

  • For a smooth journey, arrive at the airport two hours ahead of international flights and an hour before domestic departures. This will give you enough time to board your ORD to TYS flight.

  • During popular months such as August, it's a good idea to get to the airport earlier. Plan to arrive two hours before a domestic departure and four hours ahead for international flights when you travel during peak periods in general.

  • American Airlines is your gateway to exploring Knoxville (and maybe even some other great corners of United States!). Browse the direct flights from O'Hare International Airport to McGhee Tyson Airport offered by this popular airline.

  • American Airlines is the top choice for travelers on this route.

  • With 76.67% of services landing as planned, United Airlines is the most punctual carrier operating ORD to TYS flights.

  • Think about adding a stopover when booking your ticket from O'Hare International Airport to McGhee Tyson Airport. Just deselect 'Direct flights only' to break up your journey, or perhaps see a new city along the way. Here are some options between ORD and TYS:

    • Hartsfield-Jackson Atlanta International Airport

    • Charlotte Douglas International Airport

    • Washington Dulles International Airport

How to find the cheapest flights from O'Hare International Airport (ORD) to McGhee Tyson Airport (TYS)

  • The lowest price we've found for a one-way O'Hare International Airport to McGhee Tyson Airport flight is AED 409. A round-trip fare right now is AED 819. Depending on the availability when you book, these fares can change.

  • Book six months before traveling. After looking at the numbers on our calendar, this is how far you should book ahead to find cheap tickets from ORD to TYS.

  • May is the cheapest month for flights from O'Hare International Airport to McGhee Tyson Airport. If you need to travel at a different time of year, the 'Whole month' tool will give you the lowest prices across every month.

  • Cut down on the time spent looking for cheap flights from ORD to TYS by setting up a Price Alert. You'll get an email or push notification on the app when a new discounted fare appears.

  • Tailor your flights using filters. Pick your arrival and departure times, airlines and total journey duration. You can also sort your results by 'Fastest,' 'Cheapest' or 'Best' flights from O'Hare International Airport to McGhee Tyson Airport.

Handy information about O'Hare International Airport (ORD)

  • ORD is located at 10000 West O'Hare.

  • When it comes to O'Hare International Airport's on-time performance, 74.85% of flights complete their journey on time.

  • To get to O'Hare International Airport from central Chicago, it takes around 35 minutes if you're going by car. Of course, this depends on traffic. It's approximately 40 kilometers from the airport to the city center.

  • Catching public transport? You can expect a journey time of around 55 minutes.

  • Looking for a convenient hotel close to ORD? If you're boarding an early flight from O'Hare International Airport to McGhee Tyson Airport, these stays will have you sleeping moments from your departure gate:

Arriving at McGhee Tyson Airport (TYS)

  • Reserve a hotel near TYS if you're catching a late O'Hare International Airport to McGhee Tyson Airport flight. Choose one of these accommodation options and avoid the hassle of a long transfer:

  • Grab a McGhee Tyson Airport rental car and explore Knoxville and beyond with your own set of wheels. Budget, Alamo and Avis are leading providers to choose from here.

  • For the best deal, reserve your vehicle from McGhee Tyson Airport about three weeks before you travel.

Getting from McGhee Tyson Airport (TYS) to central Knoxville

  • TYS is located at 2055 Alcoa Highway.

  • McGhee Tyson Airport is roughly 23 kilometers from the center of Knoxville. The drive time takes about 20 minutes.

When to fly to McGhee Tyson Airport (TYS)

  • The quietest month for a flight from O'Hare International Airport to McGhee Tyson Airport is February, while July is the busiest. Choose the ideal time to go to Knoxville based on whether you prefer a bustling atmosphere or a more laid-back vibe.

  • The warmest month in Knoxville is July, with the temperature ranging between 17ºC (63ºF) and 32ºC (90ºF). Book your flights from O'Hare International Airport to McGhee Tyson Airport in this month if this is the type of weather you like.

  • January has average temperatures of between -6ºC (21ºF) and 11ºC (52ºF). Look for cheap tickets from ORD to TYS sometime around then if you'd rather travel in cooler conditions.

Explore more of United States

  • You've seen Knoxville, now it's time to discover more of United States. Journey around 451 kilometers north to Columbus to tick off its top attractions. From Franklin Park Conservatory and Botanical Gardens to Ohio Statehouse and German Village, you've got a jam-packed schedule ahead.

  • If you want to check out another major destination in United States, head for Indianapolis, about 467 kilometers north-west of Knoxville. The Children's Museum of Indianapolis, Indianapolis Museum of Art and Indianapolis Zoo are among the biggest draws.

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.